Pelvic Inflammatory Disease (PID)

Doses are oral and for adults unless otherwise stated. Visit the Health Products Regulatory Board website or the printed Irish Medicines Formulary for drug SPCs, dosage, contraindications, interactions, or IMF/BNF/BNFC/MIMS. See guidance on dosing in children for quick reference dosage/weight guide.

Letters indicate strength of evidence range from A+ (systematic review) to D (informal opinion). Statins can interact with some antibiotics and increase the risk of rhabdomyolysis. Amiodarone and drugs which prolong the QT interval can interact with many antibiotics. Many antibiotics increase the risk of bleeding with anticoagulants. Please refer to our Drug Interactions Table for further information.


Comments

  • Essential to test for N. gonorrhoea (as increasing antibiotic resistance) and chlamydia.
  • Microbiological and clinical cure are greater with ofloxacin than with doxycycline.A+
  • If severe PID or suspicion of tubo-ovarian abscess, inpatient admission may be required.
  • Refer patient/contacts to STI clinic.

NoteSTI clinics may also be known as STD, GUM and GUIDE clinics


Treatment

See guidance on dosing in children for quick reference dosage/weight guide.

Treatment Dose TX Duration
ceftriaxone
PLUS
metronidazole AND
ofloxacinB
500 mg IM

400 mg BD
400 mg BD
Single dose

14 days
14 days
OR
ceftriaxone
PLUS
metronidazole AND
doxycyclineB
500 mg IM

400 mg BD
100 mg BD
Single dose

14 days
14 days

Patient Information

We recommend patients use the website developed by HSE/ICGP/IPU partnership www.undertheweather.ie for tips on how to get better from common infections without using antibiotics, what you can do for yourself or a loved one and when to seek help.

The HSE Health A-Z website provides patient information on many hundreds of conditions and treatments.

Reviewed June 2016


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