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Causes - Fertility problems

Many things can affect fertility, including health conditions and lifestyle factors.

Men and women can have fertility problems. These problems can often be resolved by treating the cause.

Causes of infertility in women

Many things can cause fertility problems in women, including:

  • ovulation problems
  • endometriosis
  • pelvic infections
  • lifestyle factors
Ovulation problems

If your ovaries do not release an egg each month, you may have ovulation problems. Ovulation problems can affect your fertility.

You may have an ovulation problem if you have:

Causes of ovulation problems include:

Endometriosis

Endometriosis is a condition where tissue similar to the lining of the womb grows in other places. For example, your ovaries or the lining of your tummy.

Endometriosis causes fertility problems for some women. Endometriosis can damage the ovaries and cause adhesions (scarring) in the pelvis or around your fallopian tubes.

Damaged or blocked fallopian tubes

Fallopian tubes are the 2 tubes that connect your ovaries to your womb.

Your fallopian tubes can become damaged, blocked or scarred by:

  • pelvic inflammatory disease (PID)
  • pelvic or abdominal (tummy) surgery
  • ectopic pregnancy - you may need to have a tube removed

Surgery to repair your fallopian tubes may help you to become pregnant. But this surgery is not suitable for all women. Your doctor may recommend IVF or other fertility treatments.

Scarring from surgery to your cervix

Major surgery to your cervix may cause scarring. For example, surgery to remove cancer cells. Scarring can affect your ability to get pregnant.

Treatment such as a large loop excision of the transformation zone (LLETZ) is not likely to cause fertility problems.

Cervical cancer treatment

Health conditions and treatments

Health conditions that may affect female fertility include:

Certain medicines and treatments may also affect your fertility.

These include:

Do not stop taking a prescribed medicine without talking to your GP first.

Tell your GP about any non-prescription or herbal medicines you take.

Fibroids

Fibroids are benign (non-cancerous) tumours that grow in the muscle wall of your womb. Depending on their location, they may cause fertility problems.

Fibroids may:

  • stop a fertilised egg from attaching to your womb
  • block a fallopian tube
  • stop sperm from reaching the egg - this is rare
Cervical mucus problems

When you're ovulating, mucus in the neck of your womb (the cervix) becomes thinner. Thinner mucus is easier for sperm to swim through.

If there's a problem with your mucus, it can make it harder for the sperm to get into your womb.

Problems with sex

Problems with sex for women include:

  • vaginismus (not being able to have vaginal sex)
  • a loss of sex drive
  • pain during sex

If you or your partner have problems with sex, it can be difficult for your relationship. Talk about your problems with your GP as soon as possible.

Causes of infertility in men

The most common cause of fertility problems in men is problems with sperm.

Sperm may:

  • be low in number
  • not be in your semen at all
  • not be as good at swimming or moving as they should be
  • have an unusual shape that makes it harder for them to move or get inside the egg
Low sperm count or poor-quality sperm

There are many things that can cause problems with your sperm count or quality.

These include:

  • previous cancer treatment
  • lifestyle causes
  • testicles that did not drop properly as a baby
  • issues with your testicles because of surgery, enlarged veins (varicocele) or tumours
  • medical conditions such as a thyroid problem or poorly-controlled diabetes
  • hormonal problem such as hypogonadism - where you make little or no testosterone
  • genetic problems such as Klinefelter syndrome
  • your testicles overheating
Problems with sex

Problems with sex for men include:

  • problems getting an erection (erectile dysfunction)
  • ejaculation problems such as retrograde ejaculation (when sperm moves into the bladder instead of outside the penis)
  • difficulty having an orgasm

If you or your partner have problems with sex, it can be difficult for your relationship. Talk about your problems with your GP as soon as possible.

Health conditions and treatments

Health conditions that may affect male fertility include:

  • cancer
  • thyroid problems
  • poorly controlled diabetes
  • cystic fibrosis
  • spina bifida
  • any chronic illness that impacts your health

Certain medicines and treatments may also affect your fertility.

These include:

  • cancer treatments such as radiotherapy and chemotherapy
  • anabolic steroids
  • testosterone medicines
  • some anti-psychotic medicines and antidepressants
  • some epilepsy medicines
  • some blood pressure medicines
  • large doses of non-steroidal anti-inflammatory drugs (NSAIDs) - such as ibuprofen or aspirin
  • some herbal and alternative medicines
  • some medicines to treat auto-immune disorders

Do not stop taking a prescribed medicine without talking to your GP first.

Tell your GP about any non-prescription or herbal medicines you take.

Lifestyle factors that can affect your fertility

There are lifestyle factors can affect male and female fertility.

Age

Getting older affects your fertility, especially in women.

Female fertility starts to reduce from age 30. As you get older, the number and quality of your eggs reduce.

Male fertility may start to reduce around age 45. You may produce less sperm and your sperm quality may not be as good.

Age and trying for a baby

Weight

Weight can affect your fertility. Women who have excess weight or underweight may stop ovulation (production of eggs).

Obesity can affect the number and quality of a man's sperm.

Healthy weight when trying to get pregnant

Obesity

Smoking

Smoking and being exposed to smoke can strongly affect fertility.

Women who smoke are more likely to have fertility problems and take longer to conceive. Smoking can also damage a man’s sperm.

Get help to quit smoking

Alcohol and drugs

Alcohol use in women can disrupt the balance between hormones such as testosterone, oestrogen and progesterone. Hormone imbalance may affect ovulation and the menstrual cycle, and make it harder to conceive.

Drinking too much alcohol can affect the quality of a man's sperm.

Using drugs can also affect your fertility. For example, regular cannabis use can affect sperm quality and how much sperm you have.

How alcohol affects your sex life and fertility

Environment

Being around some pesticides, solvents, metals and high air temperatures may affect fertility, particularly in men.

Unexplained infertility

Sometimes there’s no known cause of fertility problems (unexplained infertility).

You can still get fertility treatment if no cause is found for your fertility problems.

Page last reviewed: 04/08/2026
Next review due: 04/08/2029