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Treatment - Alzheimer's disease

Treatment for Alzheimer's symptoms includes:

You can also get support to help you and your family cope with everyday life.

But there is no treatment that will cure Alzheimer's.

Medicines for memory difficulties

Medicines can help improve your memory or help symptoms. But not everyone responds or continues to respond over time to the medicines.

See the patient information leaflet that comes with your medicine for a full list of side effects.

Non-urgent advice: Find your patient information leaflet

Your patient information leaflet is the leaflet that comes with your medicine. You can find a digital version of the leaflet online.

How to find your patient information leaflet online

Report side effects

You can report any suspected side effects to the Health Products Regulatory Authority (HPRA): report an issue - hpra.ie

Acetylcholinesterase (AChE) inhibitors

These medicines increase the levels of AChE. This is a substance in the brain that helps nerve cells communicate with each other. AChE levels drop as brain cells become damaged and die in Alzheimer's disease.

Types of AChE inhibitors include:

  • Donepezil
  • Galantamine
  • Rivastigmine

These are usually prescribed by a:

  • psychiatrist
  • geriatrician (a doctor who specialises in the health of older people)
  • neurologist (a brain and nervous system expert)

Sometimes they can be prescribed by a GP.

You can keep taking AChE inhibitors as Alzheimer's progresses, if you do not have any side effects from them. There is no difference in how well each of the 3 different AChE inhibitors work. Some people respond better to certain types or have fewer side effects.

Side effects of AChE inhibitors

These can include:

  • nausea (feeling sick)
  • vomiting (getting sick)
  • loss of appetite

The side effects usually get better after 2 weeks of taking the medicine. If not, you may need to swap to another type.

Memantine

Memantine is usually prescribed for moderate to severe Alzheimer's disease.

Side effects are usually temporary and can include:

  • headaches
  • dizziness
  • constipation

Medicines for slowing early Alzheimer's

A disease-modifying therapy (DMT) is a type of medicine.

Scientists and researchers are finding out more about how DMTs slow Alzheimer's disease found at its earliest stages.

If your Alzheimer's disease was diagnosed early using a specialist test ask your healthcare team if there are any clinical trials you can take part in. Clinical trials are research studies that help you access new treatments.

DMTs do not slow other types of dementia.

Medicines to treat other symptoms and behaviour

You may be prescribed antipsychotic medicines, antidepressants or other medicines to treat non-cognitive symptoms of dementia (NCSD).

These medicines are prescribed 'off-label'. This means they are not licensed for that use. It is OK for a doctor to do this but they must give you and anyone who helps you make decisions a reason for prescribing them.

They must also tell you the risks and benefits. They will need to give you and anyone who cares for you information on side effects.

Antipsychotic medicines

Antipsychotic medicines may be prescribed to help someone who shows ongoing aggression or extreme distress.

These are only prescribed for people with moderate to severe Alzheimer's disease where there's a risk of harm to themselves or others.

How antipsychotic medicines work

Antidepressants

Antidepressants are sometimes prescribed if you have severe anxiety as part of your Alzheimer's disease. It's only prescribed if your specialist thinks your anxiety is caused by depression.

About antidepressants

Therapy for memory problems

Therapy and activities can play an important role in helping people live well with Alzheimer's.

Cognitive stimulation therapy

Cognitive stimulation therapy involves taking part in activities that help with thinking and memory.

These include:

  • talking about past and present events and topics of interest
  • word games and puzzles
  • music
  • baking
  • gardening

These are usually done in small groups for around 45 minutes at least twice a week.

Cognitive rehabilitation

Cognitive rehabilitation involves working with a trained professional and a relative or friend.

The aim is to achieve a personal goal, such as learning to use a mobile phone or other everyday tasks.

The focus is not on improving your memory, but helping you to do the things you need to do in your everyday life. It works by getting you to use the parts of your brain that are working to help the parts that are not.

Information and support programmes (courses)

There are information and support programmes (courses) for people with dementia, family carers or both. They give you information and support to better understand and cope with difficulties.

These are usually done in small groups for 2 hours a week, for 4 to 8 weeks.

Therapies and activities that can help support you

The type of therapy or activity will depend on your:

  • symptoms
  • interests
  • stage of dementia

Therapies and activities include:

  • music therapy
  • art therapy
  • aromatherapy
  • validation therapy (a type of therapy focusing on your emotions)
  • reality orientation
  • physical exercise
  • multi-sensory stimulation

Reminiscence and life story work

Reminiscence work involves talking about things and events from your past. It usually involves using props such as photos, your favourite music or things you own.

Life story work involves keepsakes from childhood to the present day, such as photos or notes. It can be either a physical book or a digital version.

Help and support

There are other supports in your community that can help you live as well as possible with Alzheimer's.

You can get support from:


Content supplied by the NHS and adapted for Ireland by the HSE

Page last reviewed: 8 April 2026
Next review due: 8 April 2029