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It is a mandatory requirement for all Serious Adverse Reactions (SAR) and Serious Adverse Events (SAE) to be reported to the National Haemovigilance Office (NHO) as required by the EU directive 2002/98/EC. All transfusion reactions reported and investigated will be forwarded to the NHO.
On discovery of a suspected transfusion reaction:
- Stop transfusion of blood product immediately where a suspected reaction has occurred and verify patient ID, ABO group of patient and donor unit immediately.
- Medical advice should be sought immediately from the patient’s team and/or the haematology team.
- Contact the Blood Transfusion laboratory during both routine and on-call hours.
- Contact the Haemovigilance Officer during routine hours.
Laboratory Investigation
When a transfusion reaction is suspected it has to be reported using the ‘Report of a Suspected Adverse Transfusion Reaction/Event’ form WRH-BT-HF-006.
This outlines sample requirements and patient transfusion details required for the investigation to be carried out in the laboratory including –
- Implicated Unit with attached giving set
- Repeat Group & X-match sample
- Blood Cultures on the patient if temp rise ≥ 39oC or ≥ 2oC from base line or suspicion of bacterial contamination
- Where indicated Blood culture on unit performed in laboratory
- Full Blood Count
- Renal Profile
- MSU
- Haemolytic screen
