Empiric antibiotic treatment should be directed against chlamydia, gonorrhoea and anaerobic organisms. Outpatient treatment with a combination of oral and IM antibiotics is appropriate for the majority of cases.
Admission to hospital and parenteral therapy is indicated in patients with evidence of sepsis, those unable to tolerate oral therapy, those likely to require surgical intervention (for example tubo-ovarian abscess).
Patients with a positive Mycoplasma genitalium result should be referred to a specialist GUM clinic. Please refer to the chlamydia and gonorrhoea pages for further management information.
Reviewed June 2021