Doses are oral and for adults unless otherwise stated. Visit the Health Products Regulatory Authority website for drug SPCs, dosage, contraindications, interactions, or IMF/BNF/BNFC/MIMS. See guidance on dosing in children for quick reference dosage/weight guide. Letters indicate strength of evidence range from A+ (systematic review) to D (informal opinion). Statins can interact with some antibiotics and increase the risk of rhabdomyolysis. Amiodarone and drugs which prolong the QT interval can interact with many antibiotics. Many antibiotics increase the risk of bleeding with anticoagulants. Please refer to our Drug Interactions Table for further information.
Comments from the Expert Advisory Committee
- Assess using the CRB-65 score (Confusion, Respiratory rate ≥ 30/min, BP ≤90/60, Age ≥ 65)
- Start antibiotics immediately
- Avoid tetracyclines in pregnancy.
- Low doses of penicillins are more likely to select out resistance.
- The quinolones ciprofloxacin and ofloxacin have poor activity against pneumococci. However, they do have use in PROVEN pseudomonal infections.
- Moxifloxacin and Levofloxacin have some anti-Gram-positive activity but should not be used as first line treatment
- Individuals at risk of influenza and pneumococcal disease should be followed up for vaccination at convalescence in line with national immunisation guidelines.
Treatment Table - Community Acquired Pneumonia
Click here for the full table in PDF
See guidance on dosing in children for quick reference dosage/weight guide.
The HSE Health A-Z website provides patient information on many hundreds of conditions and treatments.
We recommend patients use the website developed by HSE/ICGP/IPU partnership www.undertheweather.ie for tips on how to get better from common infections without using antibiotics, what you can do for yourself or a loved one and when to seek help.
Reviewed October 2018