Doses are oral and for adults unless otherwise stated. Visit the Health Products Regulatory Board website or the printed Irish Medicines Formulary for drug SPCs, dosage, contraindications, interactions, or IMF/BNF/BNFC/MIMS. See guidance on dosing in children for quick reference dosage/weight guide.

Letters indicate strength of evidence range from A+ (systematic review) to D (informal opinion). Statins can interact with some antibiotics and increase the risk of rhabdomyolysis. Amiodarone and drugs which prolong the QT interval can interact with many antibiotics. Many antibiotics increase the risk of bleeding with anticoagulants. Please refer to our Drug Interactions Table for further information.

Comments from Expert Advisory Committee

  • Most bacterial infections are self-limiting (64% resolve on placeboA+). They are usually unilateral with yellow-white mucopurulent discharge.
  • Fusidic acid has minimal Gram-negative activity.


Treatment Dose TX Duration
If severeB+ chloramphenicol 0.5% drops
PLUS 1% ointment
2 hrly reducing to QDS when infection controlled and at night Until 48 hours after resolution
fusidic acid 1% gel BD Until 48 hours after resolution

Patient Information

We recommend patients use the website developed by HSE/ICGP/IPU partnership for tips on how to get better from common infections without using antibiotics, what you can do for yourself or a loved one and when to seek help.

The HSE Health A-Z website provides patient information on many hundreds of conditions and treatments.

Click here to view information on Conjunctivitis, allergic

Click here to view information on Conjunctivitis, infective

Reviewed June 2016