Perineal wound infection - Antibiotic Prescribing

The patient should be advised regarding correct hygiene of the perineum, particularly following episiotomy.

Drug	Dose	Duration	+/- Notes
1st choice option
Co-amoxiclav	625mg every 8 hours	7-10 days
2nd choice option / Penicillin Allergy
Clindamycin	300mg-450mg every 6 hours	7-10 days

- An information sheet on ‘Antibiotics and breastfeeding' is available from the Breastfeeding Network UK
- Further information on Antibiotics and Breast-feeding can be found on the Mother to Baby website (USA) (Search or Use Browse by Medications category).
- Visit HPSC Information Leaflets pages for the General Public, (MRSA, CRE, etc)
Safe Prescribing (visit the safe prescribing page)
Doses are oral and for adults unless otherwise stated
Dosing in children quick reference dosage/weight guide
Penicillin allergy – tips on prescribing in penicillin allergy
Renal impairment dosing table
Safety in Pregnancy and Lactation
Drug interactions table. Extensive drug interactions for clarithromycin, fluoroquinolones, azole antifungals and rifampicin. Many antibiotics increase the risk of bleeding with anticoagulants.
Visit the Health Products Regulatory Authority (HPRA) website for detailed drug information (summary of product characteristics and patient information leaflets). Dosing details, contraindications and drug interactions can also be found in the Irish Medicines Formulary (IMF) or other reference sources such as British National Formulary (BNF) / BNF for children (BNFC).

Reviewed May 2022

Related Files