Doses are oral and for adults unless otherwise stated. Visit the Health Products Regulatory Board or Irish Medicines Formulary for drug SPCs, dosage, contraindications, interactions, or IMF/BNF/BNFC/MIMS. See guidance on dosing in children for quick reference dosage/weight guide.
Statins can interact with some antibiotics and increase the risk of rhabdomyolysis. Amiodarone and drugs which prolong the QT interval can interact with many antibiotics. Many antibiotics increase the risk of bleeding with anticoagulants. Please refer to our Drug Interactions Table for further information.
Comments from Expert Advisory Committee
- Trichomoniasis is caused by the flagellated protozoan, Trichomonas vaginalis. It can infect the vagina, urethra and para urethral glands. Infection is much more common in women than in men
- In women it usually presents with a vaginal discharge which may be offensive with an associated vulvitis/vaginitis
- Men usually present as sexual contacts of women with infection. They may present with symptoms of urethritis including dysuria and urethral discharge.
- Diagnosis can be made on a wet prep of vaginal secretions (in STI clinics), culture or PCR. Trichomonas testing can be performed on the same platform (Hologic Aptima) as the chlamydia and gonorrhoea testing, and can be performed on the same sample. The Aptima specimen collection kits are available through the NVRL 'swab shop' on the NVRL website
- Testing in men on a first void urine specimen is indicated in contacts of women with trichomoniasis and in cases of persistent urethritis
- Individuals diagnosed with trichomoniasis should be offered testing for other STIs including HIV, Hepatitis B, chlamydia and gonorrhoea.
- HCV testing should be considered part of routine sexual health screening in the following circumstances: People who are HIV positive; Commercial sex workers; PWID people who inject drugs ; If indicated by the clinical history e.g. unexplained jaundice; When other risk factors for HCV are present, for example MSM. The full set of recommendations around HCV testing are available in the national HCV screening guidelines
- Testing and treatment of sexual partners is important to prevent reinfection and onward transmission. Patients should be encouraged to inform their sexual partners and avoid sexual contact with their partner until the partner is tested and treated. Further information on partner notification is available in the useful resources section.
- Test of cure should be undertaken post completion of treatment
- Trichomoniasis is a notifiable disease. The complete list of notifiable diseases and information on the notification process is available from the HPSC website
2g stat PO
|Advise patients of disulfuram reaction
with alcohol, prior to taking metronidazole
|5 to 7 day course
||Metronidazole 400mg BD
PO x 5 to 7 days
Reviewed October 2018