Recently updated content on the website
Clostridioides difficile - April 2023
- Updated antibiotic treatment guidance for community and hospital settings, including advice for patients and carers
Staphylococcal Nasal Carriage - March 2023
- Updated guidance about considerations for prescribing
Respiratory Infections 2023 Winter Season: Advice & Antibiotic Supply – April 2023
- The seasonal page “Respiratory Infections 2023 Winter Season: Advice & Antibiotic Supply” has been stood down as of 3rd April 2023. For more information on specific product shortages, please check the HPRA website.
Approach to an STI consultation in Primary Care - March 2023
- MSM Asymptomatic STI Screen Quick Reference Guide updated to reflect change in PrEP eligibility criteria. Update of links to HSE PrEP guidance webpage (HSE ‘Clinical management guidance for individuals taking HIV PrEP within the context of a combination HIV (and STI) prevention approach in Ireland’ updated in 2022)
Cellulitis - March 2023
- Updated antibiotic treatment guidance, including advice for patients or carers
Clostridioides difficile - March 2023
- New safety summary sheet for oral vancomycin including information for dispensing pharmacists on how to make extemporaneous oral solution.
Renal Impairment Antimicrobial Prescribing - February 2023
- Updated renal impairment dosing tables with new agents added (e.g. Paxlovid®) and changes to recommended doses for agents including cefalexin, fluconazole, terbinafine.
Impetigo - Feb 2023
- Updated antibiotic treatment guidance, including advice for patients or carers
Dermatophyte infections of fingernail and toenail - Feb 2023
- Updated guidance on antifungal treatment and nail sampling.
Pityriasis versicolor - Feb 2023
- Updated guidance on topical and oral antifungal treatment and skin sampling.
Infected eczema - Feb 2023
- Updated antibiotic treatment guidance for adults and children, guidance on signs and symptoms of bacterial infection and bleach baths.
Tinea capitis - Feb 2023
- Antifungal treatment for adults and children updated and guidance on skin scraping and hair samples added.
Candidiasis - Feb 2023
- Cutaneous and oropharyngeal candidiasis treatment options updated and self-management advice added.
Dermatophyte Skin Infections - Feb 2023
- Topical antifungal treatment updated, self-management advice and skin sampling guidance added.
Chickenpox - December 2022
- Prescribing considerations for antivirals, self-care measures and dosing guidance for aciclovir in children added.
Shingles - December 2022
- Prescribing considerations for antivirals, self-care measures and dosing guidance for immunocompromised patients added.
Pharyngitis / Sore Throat / Tonsillitis - December 2022
- For scarlet fever, it is advisable to treat for 10 days duration
- Amoxicillin added as a second choice treatment option
Headlice - December 2022
- Treatment application details and patient information for wet combing added.
Scabies - December 2022
- Due to ongoing supply issues with topical agents, benzyl benzoate has been added as a third-line option. For treatment-resistant scabies ivermectin dosing guidance included.
Conjunctivitis - October 2022
- Chloramphenicol 0.5% Redidrops can be used with caution in children under 2yrs (recent HPRA update).
About Us - October 2022
- Updated details of Antibiotic Guidelines Editorial Group and contributors.
Infection Prevention and Control - October 2022
- We are delighted to launch our new infection prevention and control (IPC) webpage. This page contains some helpful guidance for managing IPC in the community along with some recommended HSEland e-learning modules for healthcare staff
UTI in Children - August 2022
- Additional clinical information provided as well as guidance on dipstick testing. Addition of co-amoxiclav as a second line agent for Upper UTI.
Upper and Lower Respiratory: Acute Cough in Children - August 2022
- A new section on the management of Acute Cough in Children (less than 3 weeks duration) has been added and includes information on appropriate management.
Lower Respiratory: Bronchiolitis in Children - August 2022
- A new section on the management of Bronchiolitis has been added and includes information on appropriate management. Bronchiolitis is generally a self-limiting disease usually not requiring investigation or treatment.
HSE antimicrobial stewardship (AMS) guidance for all healthcare settings – August 2022
- New AMS guidance for all healthcare settings published
- Am of the document is to provide support and guidance to AMS teams, healthcare facility managers, and the individual healthcare worker by providing the evidence, expert guidance, and tools they need to initiate and sustain AMS programmes.
- Provides guidance to the development of curricula, educational courses, and training programmes
Antimicrobial stewardship – August 2022
- Updated content
- Updated AMS patient resources, resources for healthcare professionals and audit tools
- New antimicrobial explainer infographic
Otitis Externa - August 2022
- new guidance on treatment of acute otitis externa.
- advice of self-care and how to apply ear drops.
Otitis Media in Children - August 2022
- Additional clinical information provided.
Lower UTI and Asymptomatic Bacteriuria in Pregnancy - July 2022
- Nitrofurantoin Prolonged Release Capsules added as treatment option
- Caution added re dosing/frequency for the two different formulations of nitrofurantoin available- these are not interchangeable
Nipple and breast thrush - July 2022
- Treat both mother and baby even if one of pair has no symptoms
- Nystatin added as treatment option in infants
- Miconazole for infants information updated to include dosing advice, risk of choking in infants < 4 months. Additional counselling required if prescribed in infants < 4 months.
Antimicrobial use in Residential Care Facilities - April 2022
- Report from Point Prevalence Survey on Antimicrobial Use in HSE Mental Health Residential Care facilities, Nov 2021- Jan 2022 now available. Check out the ‘Prescribing in long-term care facilities/nursing homes’ section
Prescribing for Children - March 2022
- Additional clinical information provided including guidance on the management of pain and discomfort in children, with new paracetamol and ibuprofen dosing tables. The addition of new dosing tables for doxycycline and metronidazole as well as updated dosing tables for all other antibiotics recommended for children in the guidelines.
Otitis Media in Children - March 2022
- Additional clinical information, paracetamol and ibuprofen paediatric dosing tables, and, the addition of a second choice antibiotic option.
Community Acquired Pneumonia in Children - March 2022
- Additional clinical information provided as well as updated treatment tables. Doxycyline, for certain patients, is now recommended as a 2nd line option from 8 years of age.
UTI in Children - March 2022
- Additional clinical information provided as well as guidance on dipstick testing.
Azithromycin prophylaxis - March 2022
- New consensus guidance for use of azithromycin prophylaxis in reducing exacerbations of severe COPD, bronchiectasis and asthma in adults endorsed by the National Antimicrobial Stewardship Advisory Group.
- Includes initiation criteria and baseline assessment recommendations. It should be initiated by a consultant in respiratory medicine or a consultant with a special interest in respiratory medicine.
- Recommended review every 6-12 months and if there is no evidence of clinical benefit or there is evidence of adverse effects, it should be discontinued.
Lower Respiratory, Pneumonia and Aspiration Pneumonia in Nursing Homes / Residential Care Facilities - March 2022
- New guideline for antibiotic treatment of pneumonia and aspiration pneumonia in nursing homes/ residential care facilities.
- Recommendations take into consideration older age, polypharmacy, dysphagia and renal impairment.
- Empiric antibiotic treatment for aspiration pneumonia generally does not require cover for anaerobic organisms.
- Drive for five: If antibiotics warranted, the recommended duration to treat is 5 days therapy.
Genital Conditions, Chlamydia - March 2022
- Update on use of Azithromycin therapy for chlamydia- only recommended if doxycycline contra-indicated. If indicated, stat dose of azithromycin not recommended - 3-day course is required.
Skin Conditions: Scabies - February 2022
- General advice for diagnosis and management of scabies enhanced, with the inclusion of images to aid diagnosis.
- Technique of topical application of products added including dosing and contact time.
- Patient Information Leaflet added.
Genital Conditions - February 2022
Approach to an STI consultation in Primary Care
- New section on Vaginal discharge- includes Quick reference guide for Vaginal discharge (Bacterial Vaginosis, Vaginal Candidiasis and Trichomoniasis)
- Patient resources section consolidated
Candida, Genital Thrush
- Updated treatment recommendation for recurrent candidiasis in pregnant women
Skin/Soft Tissue: Hidradenitis Suppurativa - January 2022
- Content updated and expanded with Hurley system of staging for HS added with images
- Treatment options updated as per staging
- Lymecycline added as an oral treatment option for papules or nodules associated with Hurley stage I or mild Hurley stage II.
Influenza: December 2021
COVID-19 acute respiratory infection (Adults) Dec 2021
- This guidance has been reviewed and the “Interim Guidance on Potential Role of Inhaled Budesonide for Persons in Community with COVID-19” has been removed.
- Inhaled budesonide should no longer be considered a potential treatment option for individuals with COVID-19 infection.
Epididymo-orchitis: December 2021
- Additional guidance on diagnosis and referral
Acute Prostatitis: December 2021
- Additional guidance on symptoms, diagnosis and STI screening if relevant.
Rosacea: December 2021
- Significant update. New content for examination, diagnosis and images added to aid diagnosis.
- New guidance on dosage, duration, and place in therapy for topical and/or oral agents for moderate and severe papules/pustules.
- For moderate papules/pustules, topical ivermectin or azelaic acid recommended.
- For severe papules/pustules, topical ivermectin plus low-dose doxycycline (or lymecycline) recommended.
- Guidance on use of Brimonidine for temporary treatment of redness added.
Acne Vulgaris: December 2021
- Significant update. New content for examination, diagnosis and images added to aid diagnosis and staging.
- New guidance on dosage, duration, and place in therapy for topical and/or oral agents for mild, moderate and severe acne.
- For mild acne, all treatment options are topical with Benzoyl Peroxide recommended first-line. Other options listed dependent on presence of comedones and/or inflammatory lesions (pustules).
- For moderate acne not responding to topical treatment, use of oral lymecycline in combination with a non-antibiotic topical is recommended first-line. Oral antibiotics are not recommended in combination with topical antibiotics. Oral antibiotics should be reviewed and limited to 3months if possible (max 6 months).
- Referral considerations for Isoretinoin added.
Asymptomatic Bacteriuria in Pregnancy: Section update December 2021
Lower UTI in Pregnancy: December 2021
- Warning signs added for when to consider Upper UTI/ Pyelonephritis
- Cefalexin (2nd choice treatment option) dose changed to 500 mg every 8 hours for 7 days
- Fosfomycin guidance on when to prescribe in pregnancy and directions on how to take fosfomycin for best absorption
What’s new – Lyme disease November 2021
- Additional guidance added on when to test, when to treat and when to refer
- Update on recommended duration of antibiotic treatment
- New guidance of prophylaxis of Lyme disease in children
- Section added on safety of doxycycline in children and prescribing/administration of dispersible doxycycline in children
Toolkit for Antimicrobial Stewardship in Residential Care Facilities November 2021
- A collection of supporting tools, documents and practice points for AMS in residential care
- NEW Decision-aid for Management of Suspected UTI
- HSELand module for Prevention & Management of UTI signposted
- Report of findings of Extended PPS of Antimicrobial Use in HSE RCFs for Older Persons published (includes data for CHO 2, 6,7, 9)
Upper and Lower Respiratory Tract infections: November 2021
- Guidelines reviewed and updated for Sinusitis, Pharyngitis/Sore throat, Acute Bronchitis/Cough, Infective exacerbation of COPD, CAP in Adults, COVID-19
- Drive for five: If antibiotics are warranted, all these indications now recommended to treat with 5 days therapy.
- All CAP treated in community now recommended at duration of 5 days including CRB-65 score 1-2 (reduced from 7days).
- COPD: Link to new National NCEC Clinical Guideline added.
NEW: Position statements for ‘The use of dipstick urinalysis to assess for evidence of urinary tract infection in adults’. September 2021:
- Consensus best-practice statements for the use of dipstick urinalysis endorsed by the National Antimicrobial Advisory Group.
- Inappropriate use of dipstick urinalysis can lead to unnecessary antibiotic prescribing which does not benefit the patient and may cause considerable harm.
- Best-practice statements include advice on the use of dipstick urinalysis to assess for evidence of UTI in several patient cohorts such as:
- Females (non-pregnant) <65yrs
- Males <65yrs
- Pregnant females
- All persons >65yrs
- All persons with a urinary catheter
- Asymptomatic persons
Treatment of urinary tract infections in adults reviewed and updated, September 2021:
Guidelines on genital conditions updated July 2021, of particular note:
- Chlamydia: Additional information on rectal infection with invasive chlamydia types (Lymphogranuloma (LGV) types), test of cure and window period
- Anogenital warts: Updated HPV vaccine recommendations and drug treatment option
- Genital Herpes: Patient resources updated
- Candida: Update on use of high vaginal swab and treatment options
- Gonorrhea: Referral criteria to GUM clinic; window period; treatment options and resistance information
- Trichomoniasis: Updates on referral criteria; window period, test of cure information; drug counselling points
- Bacterial Vaginosis: Update on use of high vaginal swab and drug counselling points
- PID: Referral criteria to GUM clinic, including Mycoplasma genitalium guidance
Approach to an STI consultation in Primary Care, July 2021
- Incudes quick reference guides for asymptomatic screening in primary care
- Additional information on sexual history and STI testing
- Window period explained, lookback periods/partner notification information listed for the different STIs
- Also includes information on non-specific urethritis, HIV pre-exposure prophylaxis and genital care resources available for patients
- Links to further resources for healthcare professionals and patients
Conjunctivitis: May 2021
- The use of Chloromycetin® Eye Drops contraindicated in children under 2 years (due to presence of excipient Boron).
- Printable content added regarding self-care advise for the patient presenting with sticky eye/conjunctivitis.
- Content added regarding when to swab, refer or seek specialist input.
Antimicrobial Stewardship in Community July 2021
Suspected Meningococcal Disease May 2021
- Section updated with administration information added
COVID-19 acute respiratory tract infection May 2021
- Interim guidance on role for inhaled budesonide.
Oral Infections (previously Dental infections) March 2021
- Treatment of oral and dental infections revised and updated.
Acute Dento-Alveolar Abscess:
- If antibiotics are indicated, phenoxymethylpenicillin now preferred option instead of amoxicillin (unless adherence likely to be challenging)
- Additional guidance provided regarding eradication of bacterial or fungal reservoir.
- Terbinafine 1% provided as option for patients on warfarin where use of miconazole should be avoided.
- Additional guidance provided regarding management of breastfeeding mother for an infant with oral candida infection.
- Use of oral fluconazole should be reserved for severe cases or those who are non-responsive to first-line therapies.
- All patients who require fluconazole should be seen by their GP for investigation into possible underlying causes.
Gastro Conditions March 2021
- Name change: Clostridium difficile → Clostridioides difficile. Criteria for assessing non-severe versus severe C. Diff added.
- Removal of piperazine as a treatment option – no longer available in Ireland
- Additional information re. 2nd dose of mebendazole administered after 2-4 weeks
- Mebendazole is unlicensed in < 2year olds but some evidence to support use at > 6 months of age.
- Change from Ciprofloxacin to Azithromycin as recommended antibiotic if treatment is required.
- Additional clinical information and links have been added.
Respiratory tract infections February 2021
- For pregnancy, if macrolide considered necessary, azithromycin added as an option for all trimesters.
Pregnancy and Postpartum infections February 2021
- Additional Patient information resources added to all sections
- Additional Healthcare Professional information resources added to Prescribing Antimicrobials in Pregnancy and Lactation page
Asymptomatic Bacteriuria in Pregnancy new content! February 2021
- Advice on when and how to test for and treat asymptomatic bacteriuria in pregnancy
- Urine culture remains the gold standard for detection of asymptomatic bacteriuria
- Dipstick testing is not sufficient to screen for bacterial UTIs in pregnancy.
- Drug treatment based on the bacteria isolated in urine culture and trimester of pregnancy
Nipple and breast thrush: February 2021
- The use of all-purpose nipple ointment is not recommended as treatment option.
- Additional information points on use of miconazole for mother and baby.
Helicobacter pylori: December 2020
- H. Pylori duration of treatment for all treatment regimens has been increased from 7 days to 14 days in line with published national guidelines.
- A Bismuth quadruple regimen, if available, has been added as a 1st line treatment option. A levofloxacin regimen has also been added but should be reserved as a 2nd line option for failed treatment eradication.
Pharyngitis/ sore throat / tonsillitis: December 2020
- Cefalexin is an option for non-severe penicillin allergy, if antibiotic deemed necessary.
- Majority are viral however if antibiotics deemed necessary, recommended duration now 5 days (instead of 10 days)
Lyme Disease, Nov 2020
- Criteria for post-exposure prophylaxis updated
Seasonal Influenza, Nov 2020
- Seasonal Influenza page updated for 2020/2021 season.
- Duration of treatment for oseltamivir in immunocompromised patients changed to 10 days.
- Links to Coronavirus COVID-19 information added.
COVID-19 acute respiratory infection, Nov 2020
- Link to HSE COVID-19 repository added
- Updated re advice on penicillin allergy in pregnancy.
Drug Interactions Table update, Nov 2020
- Drug interactions information updated for Neuraminidase inhibitors
Upper Respiratory Tract Infections, Nov 2020
- Pharyngitis: Majority are viral however if antibiotics deemed necessary, recommended duration now 5 days (instead of 10 days)
- Sinusitis (adults): Majority are viral however if antibiotics deemed necessary, doxycycline (first line if penicillin allergy) can be dosed at 200mg daily.
Lower Respiratory Tract Infections Nov 2020
- Doxycycline (often first line if penicillin allergy) can be dosed at 200mg daily across the range of lower respiratory tract infections.
- Duration of recommended therapy for community-acquired pneumonia reduced; 5 days for CRB-65 score 0 (instead of 5-7days), 7 days for CRB-65 score 1-2 (instead of 7-10 days)
- Recommend higher dose amoxicillin (1g tds as opposed to 500mg tds) for community-acquired pneumonia CRB-65 score 1-2
New content to support deprescribing UTI prophylaxis, Nov 2020
- All UTI prophylaxis should be reviewed at 3-6mths with a view to stopping as many patients can stop without a return of symptoms.
- There is no evidence of additional benefit beyond 3-6 months but there is significant evidence of harm.
About Us, Nov 2020
- Contact details for community antimicrobial pharmacists added.
- List of contributors updated
UTI in Long Term Care Residents over 65, Nov 2020
Diagnosis & Management of Urinary Tract Infection (UTI) in Residential/Long Term Care/Nursing Home Residents (non-catheter associated)
- Nitrofurantoin now first choice for uncomplicated UTI (Trimethoprim removed), or Cefalexin if nitrofurantoin unsuitable.
- Recommended duration for uncomplicated UTI is 3 days for females, 7 days for males
- Cefalexin now recommended first choice for acute pyelonephritis (duration 7-10 days)
Diagnosis & Management of Catheter-Associated Urinary Tract Infection (CA-UTI) in Residential/Long-Term Care/Nursing Home Residents
- Non-specific signs & symptoms of CA-UTI in elderly residents included (but consider COVID-19)
- Cloudy urine or foul-smelling urine do not indicate an infection in absence of signs and symptoms of infection.
- CA-UTI to be treated like an upper UTI, with cephalexin 1st choice (unless guided otherwise by culture). Use of nitrofurantoin or trimethoprim for CA-UTI removed.
Green/Red antibiotic quality improvement initiative. Nov 2020
- Includes background information and a summary of positive key trends observed with this important quality improvement initiative.
Videos on safe Antibiotic use - Nov 2020
Renal Impairment Summary Sept 2020
- Medicines list expanded to include anti-fungals and anti-helmintics
- Advice on Fosfomycin updated (avoid if CrCl <10ml/min)
- Advice on Nitrofurantoin updated (contraindicated if CrCl <30ml/min, caution in use if CrCl 30-45ml/min)
Animal and Human Bites Sept 2020
- Content of both pages merged
- Expanded advice on general management and antibiotic prophylaxis
- Duration of prophylaxis 5 days, duration of treatment 7 days
COVID-19 acute respiratory infection May 2020
- COVID-19 is a viral infection.
Antivirals or agents with antiviral properties for COVID-19 should not be prescribed for treatment or prophylaxis in the community, unless as part of a clinical trial.
Secondary bacterial infection appears uncommon in COVID-19 patients.
Key messages from AMRIC to community prescribers March 2020
- Tips on safe us of clarithromycin, and important safety concerns for fluoroquinolones especially moxifloxacin are just some of the items covered
Recurrent UTI in Adult, Non-Pregnant Females March 2020
- This guideline refers to symptomatic culture-proven recurrent urinary tract infection (UTI)
It covers non-antimicrobial measures, antibiotic prophylaxis. It is important to remember that recurrent or persistent lower urinary tract symptoms are not always due to recurrent UTI. Other conditions such as STI, postmenopausal atrophic vaginitis and dermatological conditions often cause similar symptoms.
Antimicrobial prophylaxis should be reviewed after 3-6 months with a view to stopping